i-mass guides : Index | Classic Articles | Definitions | History | Movies | Nobel Prizes | Protocols | Resources | Techniques | Troubleshooting | Tutorials

Past Features

WWW ChemTools

  • Ion Formula by Mol. Weight
  • Isotope Pattern Calculator
  • Mass Loss Calculator
  • Periodic e-Table

WWW BioTools

  • EMBL Peptide Search - protein ID from peptide mass and sequence data
  • FindMod - post-translational modifications by peptide mass
  • GlycanMass - oligosaccharide mass from structure
  • GlycoMod - oligosaccharide structures from mass
  • GlycoSuiteDB - search database with oligosaccharide mass
  • Javascript Protein Digest - peptide digest masses
  • Javascipt Fragment Ion Generator for peptides
  • Mascot Search - peptide mass and sequence tools
  • Mowse - protein identification from peptide MS data
  • Protein Prospector - mass spectra interpretation tools
  • PROWL - identification of proteins from MS data



Life is Sweet

A controversial theory that sugar-related molecules may have seeded life on earth has been boosted by GC-mass spectrometry studies of meteorites. This space rock arrived on the infant earth around four billion years ago leading to the growth of bacteria that evolved into primitive life forms.

So-called polyhydroxylated compounds (polyols) have been found in carbon-rich asteroid fragments discovered last century in Australia and the United States, by a team from NASA's Ames Research Center. It is concluded that polyols were present on the early earth and therefore, at least available for incorporation into the first forms of life.

The idea of life's ingredients arriving on meteorites gained ground among space scientists after they were found to contain amino acids, the basics of proteins. Additional experiments showed that these acids could be chemically produced in the laboratory by combining methane and ammonia.

The polyols are a family of carbon compounds that comprise sugar, sugar alcohols and sugar acids. Polyols provide the "skeleton" for many other molecules as well as a vital energy source for cells.

The study's samples came from the Murchison meteorite, found near Melbourne, Australia in 1969, and the Murray meteorite located around 1930 on a farm in Oklahoma. Gas chromatography-mass spectrometry (GC-MS) was used to ionise and identity the polyols.

The study appears in Nature (December 2001) Volume 414, 879 - 883.

MS Journals

  • European Mass Spectrom.
  • Intl. J. of Mass Spectrom.
  • J. American Society of MS
  • J. Mass Spectrometry
  • J. MS Society of Japan
  • Mass Spectrometry Reviews
  • Rapid Communications in MS

Science Journals

  • Analyst
  • Analytical Chemistry
  • Nature
  • New Scientist
  • Science
  • Scientific American

Literature Search

  • Beilstein Abstracts
  • ChemWeb
  • Current Contents - ISI
  • PubMed - NCBI
  • PubScience - DOE

World Laboratories


Copyright www.i-mass.com. All rights reserved worldwide.

Related Links

Resource Links